![]() |
May 21, 2010, 4:38 pm
Towards synthetic lifeDNA made in a laboratory has been put into bacterial cells, which grew to follow instructions from genes in the synthetic DNA.
Source:
news.bbc.co.uk
|
What was discovered?
Synthetic DNA, which was made in a laboratory, was able to control the growth and reproduction of a bacterial cell that it was put into.
Even after replicating billions of times, each new bacterium formed contained a copy of the synthetic DNA, which continued to control the cell!
How?
DNA was made in a laboratory by copying the known DNA sequence of a certain species of bacterium.
When this synthetic DNA was put inside a host bacterial cell, it could perform just like the DNA of a normal, living bacterium. The host cell grew with characteristics just like the 'natural' one that the synthetic DNA was copied from!
Why is it important?
Being able to grow bacteria containing synthetic DNA will enable many different kinds of proteins to be made in large quantities using synthetic genes - these proteins could be developed as medicines or vaccines.
Bacteria which can help produce fuels, or clean up pollution, may also be developed using synthetic DNA.
How does DNA control a cell?
Every activity inside a living cell is controlled by proteins - many of which, called enzymes, speed up chemical reactions so that they happen fast enough for life even at low temperatures.
DNA controls what goes on inside a cell by controlling which proteins (including enzymes) are made and when.
Genes are the sequences of DNA giving instructions to make each protein.
How exactly are proteins made?
The gene is copied into a messenger RNA (mRNA) molecule in a process called transcription, and then the mRNA sequence is translated into the sequence of amino acids making up the protein with the help of ribosomes.
Watch a video of how transcription and translation happen!
Are bacteria living organisms?
yes! They are simpler than the cells that make up our bodies, but they are alive!
Their DNA is made of the same kinds of nucleotides, with the bases adenine, guanine, cytosine and thymine as ours, but there is much less of it, so it can all be packaged into just one circular chromosome. [Humans have 46 chromosomes.]
Bacterial genes make bacterial proteins using ribosomes, but the amazing thing is that bacteria can also make proteins from human genes too!
That is because the ribosomes of bacteria use the same code to translate the sequence of mRNA into the amino acids making the protein as our ribosomes! That's why the genetic code is said to be 'UNIVERSAL'.
And that is worth a little more thought...
How did life start ?
Now that's a big question!
See what Nobel laureate Jack Szostak has to say about it in this interview.
(question 9 - How would you describe the chemical origin of life?)

Current rating